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 The small intestine is a crucial component of the digestive system, responsible for nutrient absorption and digestion.

However, various disorders can disrupt its function, leading to significant health issues.

Understanding the causes, symptoms, diagnosis, and treatment of small intestinal disorders is essential for effective management and improved quality of life.


The Importance of the Small Intestine


The small intestine, comprising the duodenum, jejunum, and ileum, is responsible for most nutrient absorption.

It is lined with villi and microvilli, which increase the surface area for efficient absorption of nutrients from the digested food.

Any disorder affecting this part of the digestive tract can lead to malnutrition, weight loss, and other health complications.


celiac disease disorder - Small Intestinal Disorders: Causes, Symptoms, Diagnosis, and Treatment


Common Small Intestinal Disorders


Celiac Disease

Celiac disease is an autoimmune disorder where the ingestion of gluten leads to damage in the small intestine. Gluten, a protein found in wheat, barley, and rye, triggers an immune response that attacks the small intestine’s lining. This damage impairs nutrient absorption.



  • Diarrhea
  • Bloating and gas
  • Abdominal pain
  • Fatigue
  • Weight loss



Celiac disease is diagnosed through blood tests for specific antibodies and confirmed with an intestinal biopsy showing villous atrophy.



The primary treatment is a strict, lifelong gluten-free diet, which allows the intestine to heal and prevents further damage.


crohns disease symptoms - Small Intestinal Disorders: Causes, Symptoms, Diagnosis, and Treatment


Crohn’s Disease

Crohn’s disease is a type of inflammatory bowel disease (IBD) that can affect any part of the gastrointestinal tract but most commonly affects the ileum. It causes inflammation that penetrates the entire thickness of the intestinal wall.




  • Chronic diarrhea
  • Abdominal pain and cramping
  • Blood in stool
  • Fatigue
  • Weight loss
  • Reduced appetite



Diagnosis involves a combination of blood tests, stool tests, endoscopy, colonoscopy, and imaging studies like CT scans or MRI.



Treatment includes anti-inflammatory drugs, immune system suppressors, antibiotics, and biologics. In severe cases, surgery may be necessary to remove damaged portions of the intestine.


Small Intestinal Bacterial Overgrowth (SIBO)

SIBO occurs when excessive bacteria grow in the small intestine, disrupting normal digestion and absorption.



  • Bloating and gas
  • Diarrhea or constipation
  • Abdominal pain
  • Malnutrition
  • Unintended weight loss



SIBO is diagnosed through breath tests that measure hydrogen and methane produced by bacteria in the small intestine.



Treatment includes antibiotics to reduce bacterial overgrowth, dietary changes, and probiotics to restore a healthy balance of gut bacteria.


Intestinal Obstruction

Intestinal obstruction is a blockage that prevents food or liquid from passing through the small intestine.



  • Scar tissue from previous surgeries (adhesions)
  • Hernias
  • Tumors
  • Inflammatory diseases like Crohn’s



  • Severe abdominal pain
  • Nausea and vomiting
  • Inability to pass gas or stool
  • Swelling of the abdomen



Diagnosis involves physical examination, X-rays, CT scans, and ultrasound.



Treatment may require hospitalization with intravenous fluids, nasogastric tube insertion to relieve pressure, and surgery to remove the obstruction.

intestinal obstruction - Small Intestinal Disorders: Causes, Symptoms, Diagnosis, and Treatment


Less Common Small Intestinal Disorders


Intestinal Ischemia

Intestinal ischemia occurs when blood flow to the small intestine is reduced due to blocked blood vessels. This can cause tissue damage or necrosis.



  • Severe abdominal pain
  • Urgent bowel movements
  • Bloody stools
  • Nausea and vomiting



Diagnosis is done through imaging studies like CT angiography or magnetic resonance angiography (MRA).



Treatment may involve medications to dissolve blood clots, surgery to remove the blockage, or procedures to restore blood flow.


Whipple’s Disease

Whipple’s disease is a rare bacterial infection that affects the small intestine, leading to malabsorption.



  • Chronic diarrhea
  • Abdominal pain
  • Weight loss
  • Joint pain
  • Anemia



Whipple’s disease is diagnosed through intestinal biopsy and PCR tests to detect the presence of Tropheryma whipplei bacteria.



Treatment involves long-term antibiotics to eradicate the infection.


Diagnosis of Small Intestinal Disorders


Diagnosing small intestinal disorders typically involves a combination of the following:


  1. Medical History and Physical Examination:

 A detailed medical history and physical examination can provide initial clues about the underlying disorder.


  1. Laboratory Tests:

Blood tests can detect signs of inflammation, anemia, and other abnormalities. Stool tests may identify infections or malabsorption.


  1. Imaging Studies:

Imaging techniques like X-rays, CT scans, and MRI can reveal structural abnormalities, obstructions, and areas of inflammation.


  1. Endoscopic Procedures:

Endoscopy, including capsule endoscopy, allows direct visualization of the small intestine and can help identify lesions, inflammation, and other abnormalities.


  1. Biopsy:

Tissue samples taken during endoscopy can be analyzed to confirm diagnoses like celiac disease or Whipple’s disease.


diagnosis colonoscopy 1 - Small Intestinal Disorders: Causes, Symptoms, Diagnosis, and Treatment


Treatment of Small Intestinal Disorders


Dietary Modifications:

Many small intestinal disorders, such as celiac disease and SIBO, can be managed with specific dietary changes. A gluten-free diet for celiac disease or a low-FODMAP diet for SIBO can significantly alleviate symptoms.



  • Anti-inflammatory Drugs: Used in conditions like Crohn’s disease to reduce inflammation.
  • Antibiotics:  Used to treat bacterial infections like SIBO and Whipple’s disease.
  • Immunosuppressants:  Used in autoimmune conditions to reduce immune system activity.
  • Probiotics: Can help restore the balance of gut bacteria in conditions like SIBO.



Surgical intervention may be necessary in cases of intestinal obstruction, severe Crohn’s disease, or ischemic bowel disease. Surgery aims to remove damaged sections of the intestine, bypass obstructions, or restore blood flow.

Nutritional Support:

Nutritional deficiencies due to malabsorption are common in small intestinal disorders. Nutritional support, including supplements and specialized diets, can help address deficiencies and improve overall health.


Living with Small Intestinal Disorders


Living with small intestinal disorders can be challenging, but with the right information and strategies, individuals can lead healthy and fulfilling lives.

Understanding the nature of these disorders, their symptoms, and how to manage them is crucial for maintaining a good quality of life.


  1. Adhere to Dietary Restrictions:

 Follow dietary recommendations provided by healthcare professionals to manage symptoms and prevent complications.


  1. Regular Monitoring:

Regular medical check-ups and monitoring are essential to track disease progression and adjust treatment plans as needed.


  1. Stay Informed:

Educate yourself about your condition, treatment options, and potential complications. Staying informed empowers you to make better health decisions.


  1. Seek Support:

Join support groups or seek counseling to cope with the emotional and psychological challenges of living with a chronic illness.


  1. Maintain a Healthy Lifestyle:

Incorporate regular exercise, adequate hydration, and stress management techniques into your daily routine to improve overall well-being.

small intestinal disorders infographic - Small Intestinal Disorders: Causes, Symptoms, Diagnosis, and Treatment



Small intestinal disorders encompass a wide range of conditions that can significantly impact health and quality of life.

Early diagnosis, effective treatment, and ongoing management are crucial for improving outcomes.

By understanding the causes, symptoms, diagnostic procedures, and treatment options for these disorders, individuals can better navigate their journey toward improved intestinal health and overall well-being.

Regular communication with healthcare providers and adherence to prescribed treatment plans are key to managing small intestinal disorders successfully.


Contact Dr. Schneider

Contacting Dr. Schneider is a prudent step towards gaining comprehensive insights into colonoscopy and screening methods.


Dr. Schneider, a distinguished gastroenterologist with a wealth of experience in digestive health, is well-equipped to provide personalized guidance tailored to individual needs.


With a commitment to patient education and well-being, Dr. Schneider ensures that individuals are informed about the procedure, addressing any concerns and emphasizing the significance of regular screenings for early detection.

Talk to us today to book your appointment.

For further reading on the procedures we perform, please visit our website or contact Dr. Schneider on 011-482-3010.




The information on this website is to provide general guidance. In no way does any of the information provided reflect definitive medical advice and self-diagnoses should not be made based on information obtained online. It is important to consult a Gastroenterologist or medical doctor regarding ANY and ALL symptoms or signs including, but not limited to: abdominal pain, haemorrhoids or anal / rectal bleeding as it may a sign of a serious illness or condition. A thorough consultation and examination should ALWAYS be performed for an accurate diagnosis and treatment plan. Be sure to call a physician or call our office today and schedule a consultation.